With the rapid development of Intelligent Computing and System Simulation technologies, the applications of related technologies are gradually penetrating into various industries. The diversity and complexity of these applications have prompted the need for a specialized forum for researchers to exchange new technologies, methods and ideas in a timely manner. 2026 International Conference on Intelligent Computing and System Simulation (ICSS 2026) will be held in Changchun, China, on September 11-13, 2026. This conference aims to bring together researchers, scholars and engineers in the field of intelligent computing and system simulation to jointly discuss the current technology frontiers, application trends and future development directions.