Protein Science in Drug Discovery 2024

Generation of Antigens for Drug Discovery

Antigen production is a critical but often overlooked area of antibody and vaccine drug discovery. In a landscape where therapeutic antibody and vaccine targets grow increasingly complicated, exceptional antigen production has never been more vital. This session will explore approaches for designing and optimising antigens and how the optimal antigen can shape antibody and vaccine discovery pipelines leading to the best candidate drugs.

Protein biophysics at different stages of drug discovery

Protein biophysics has pushed forward the boundaries of drug discovery. In this session we will hear how researchers are expanding the biophysics arsenal to enable us to tackle challenging targets, understand mechanisms of action, and develop biologics and other drugs better and faster.

High-throughput in silico and experimental approaches to accelerate protein generation

Protein generation is a key for successful drug discovery. In this session we will focus on in silico design approaches, automated high-throughput experimental approaches and the interface between the two, with the aim to identify conditions for well behaving constructs and proteins to accelerate drug discovery.

Cryo-EM in Drug Discovery: From protein to structure to dynamics

The structure and motion of proteins at the atomic level are key elements of target druggability. In this session, we will explore how major advances in the field of cryo- electron microscopy have opened a window to understanding and harnessing protein structure & dynamics to develop superior drugs.