The 2nd International Symposium on Machine Learning and Social Computing (MLSC 2026) will be held from October 26 to 28, 2026, in Bangkok, Thailand. MLSC 2026 will focus on cutting-edge applications of machine learning methods in social science fields such as psychology, economics, sociology, and education, exploring how algorithmic models can analyze human behavior patterns, social dynamic evolution, and complex system decision-making. The conference covers hot topics including social computing, data-driven policy research, and human-computer interaction behavior analysis, providing opportunities for academic and industry practitioners to exchange ideas and foster collaborative innovation. We sincerely invite global scholars, technical experts, and industry practitioners to gather in Bangkok and jointly explore paradigm innovation in social science research in the intelligent era.