Strategic approaches for early clinical trials in neurodegenerative diseases

Using patient-centric trial design and biomarker insights to support confident development decisions Generating meaningful clinical insights as early as possible is a growing priority in neurodegenerative disease development. To support faster and more informed decision-making, sponsors are increasingly implementing innovative first-in-human study designs that integrate multiple objectives, streamline development pathways and enable earlier evaluation in patients. These approaches can also help address ethical and tolerability challenges that may limit traditional healthy volunteer studies. This webinar will explore the opportunities and challenges associated with these strategies, highlighting examples from neurodegenerative disease therapeutics and discuss: Getting the basics right: Study objectives and population selection Bringing the patient voice into early development Biomarkers as decision-making tools in neurodegenerative development Register for this webinar to learn how early clinical trial design, patient involvement and biomarker strategies can support more informed development decisions in neurodegeneration.

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