Ends At: 21/03/2018
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ConferenceSeries Ltd is a renowned organization that organizes highly notable pharmaceutical conferences throughout the globe.After a successful conference of Pharmaceutica 2017, ConferenceSeries Ltd is currently bringing forth 16th International Conference and Exhibition on Pharmaceutics & Novel Drug Delivery Systems (Pharmaceutica 2018) slated on March 19-21, 2018 at Berlin, Germany. The conference invites all the participants across the globe to attend and share their insights and convey recent developments in the field of Pharmaceutics and Novel Drug Delivery Systems.
Track 1: Pre-Formulation & Formulation Aspects
Pharmaceutics is the study of relationships between formulation, pharmaceutical formulation, delivery, disposition and clinical response. The inherent instability nature of a new drug will alter its desired form into undesired form when presented in a suitable dosage form with the excipient/s upon storage. In early days this process was confined only for assessing few characteristics, but today this process is being considered as a formulation strategy and hence tremendous technological advancement has been achieved in this field which enables us to save time and money through planned management system and hence impacts Pharmaceutica 2018 to be a formulation conference. Use of glorious statistical software even based on artificial neural networking is made the task of preformulation and optimization process easier. Role of preformulation studies techniques like freeze drying aspects projects the event Pharmaceutica 2018 to pose as a freeze-drying meeting in drug discovery, drug development plays a major role in pharmaceutical formulation development and the studies will help in different dosage forms design. With the increasing number of novel and specialized compounds being developed, a “one size fits all” approach to drug formulation and delivery is no longer optimal, necessitating the consideration of formulations unique to each drug. NDDS conference will discuss on Early Approaches, Present Scenario and Future Prospects of Preformulation events. There are more than 1400 sustained or controlled release drugs have been approved all over the world. Pharmaceutical conferences discuss the state-of-art technology being applied and involve advances in formulation studies.
Revenues within the global generics market reached an estimated value of $265 bin 2012, showing a growth of 9.3% throughout the year. The contribution of generics is approximately 20% of the overall international pharmaceutical market. The utilization of generic in terms of volume is higher in the US and lower in Japan, 89%, and 24% respectively.
- Track 1-1Preformulation in Drug Development
- Track 1-2Drug Formulation Considerations
- Track 1-3Major Challenges in Drug Development
- Track 1-4Physiological Drug Environment
- Track 1-5Freeze Drying
- Track 1-6Hot Melt Extrusion
Track 2: Drug Targeting and Design
The most fundamental goal in drug design is to predict whether a given molecule will bind to a target and if so how strongly. Molecular mechanics or molecular dynamics are most often used to predict the conformation of the small molecule and to model conformational changes in the biological target that may occur when the small molecule binds to it. The therapeutic response of a drug depends upon the interaction of drug molecules with a cell on cell membrane related biological events at receptor sites in a concentration-dependent manner.
Selective and effective localization of the pharmacologically-active moiety at pre-identified target(s) in therapeutic concentration, while restricting its access to non-target(s) normal cellular linings, thus minimizing toxic effects and maximizing the therapeutic index accounts from effective and efficient drug delivery.
Molecular mechanics methods may also be used to provide a semi-quantitative prediction of the binding affinity. Also, the knowledge-based scoring function may be used to provide binding affinity estimates. These methods use linear regression, machine learning, neural nets or other statistical techniques to derive predictive binding affinity equations by fitting experimental affinities to computationally derived interaction energies between the small molecule and the target.
- Track 2-1Factors influencing Drug Targeting
- Track 2-2Targeted drug delivery
- Track 2-3Nano Materials
- Track 2-4Advanced Drug Delivery
- Track 2-5RACHEL Software Package
- Track 2-6Rational Drug Design Software
- Track 2-7Role of Computers in Drug Design: Their Success and Failure
- Track 2-8Drug Design Theory
- Track 2-9Computer Aided Drug Design
- Track 2-10Rational Drug Design
- Track 2-11Recent Approaches to Drug Targeting
- Track 2-12Advances in Drug Targeting components
- Track 2-13 Nanoparticles